Sex-Dependent Decrease of Sphingomyelinase Activity During Alcohol Withdrawal Treatment
نویسندگان
چکیده
منابع مشابه
Sex-dependent decrease of sphingomyelinase activity during alcohol withdrawal treatment.
BACKGROUND In vitro and in vivo studies have demonstrated the role of the acid sphingomyelinase (ASM) in pathophysiological processes and alterations in response to ethanol exposure. Cellular and plasmatic ASM activities are increased in male alcohol dependent patients and decrease during physical withdrawal. METHODS Here, we analyzed the time course of ASM in male and also female acutely int...
متن کاملTreatment of alcohol withdrawal.
Appropriate treatment of alcohol withdrawal (AW) can relieve the patient's discomfort, prevent the development of more serious symptoms, and forestall cumulative effects that might worsen future withdrawals. Hospital admission provides the safest setting for the treatment of AW, although many patients with mild to moderate symptoms can be treated successfully on an outpatient basis. Severe AW r...
متن کاملMagnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography.
BACKGROUND Sleep electroencephalogram alterations and insomnia complaints persist after alcohol withdrawal in dependent patients and are considered strong predictors of relapse. Although disturbances of magnesium household due to alcohol consumption are well known, the relationship of magnesium metabolism and sleep disturbances has not been investigated in this patient group. We conducted an op...
متن کاملThe treatment of alcohol withdrawal.
Abrupt cessation of regular use of alcohol in a dependent person causes a withdrawal syndrome that may range from mild to extremely severe. Most patients require pharmacologic intervention, especially those with severe symptoms. Historically, the pharmacotherapy of alcohol withdrawal has involved a wide variety of agents. Benzodiazepines are currently preferred due to their consistently high de...
متن کاملTreatment of Severe Alcohol Withdrawal.
OBJECTIVE Approximately 50% of patients with alcohol dependence experience alcohol withdrawal. Severe alcohol withdrawal is characterized by seizures and/or delirium tremens, often refractory to standard doses of benzodiazepines, and requires aggressive treatment. This review aims to summarize the literature pertaining to the pharmacotherapy of severe alcohol withdrawal. DATA SOURCES PubMed (...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2014
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000362985